The C-19 Index

What It Is

The C-19 Index is an open source, AI-based predictive model that identifies people who are likely to have a heightened vulnerability to severe complications from COVID-19 (commonly referred to as “The Coronavirus”). The C-19 Index is intended to help hospitals, federal / state / local public health agencies and other healthcare organizations in their work to identify, plan for, respond to, and reduce the impact of COVID-19 in their communities.

What It’s NOT

To be absolutely clear – the C-19 Index does NOT predict who will become infected with COVID-19 or geographic locations where the virus might spread. It is meant to identify people with a heightened risk of severe complications should they become infected.
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How Protecting Our Most Vulnerable People Helps Fight COVID-19

A percent of people who become infected with COVID-19 will have severe complications, require treatment with mechanical ventilators in intensive care units (ICUs) and possibly die. To prevent this – and prevent overloading the healthcare system – we need to identify those individuals now and find practical solutions to help them “shelter in place” so they don’t need to leave their homes.

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The C-19 Index – Impact In The Community:

Medical home network logo

Largest Medicaid ACO in the country

Press Release
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healthfirst logo

HealthFirst insures 1 in 6 New Yorkers

Announcement
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impact on population health

The Science Behind The C-19 Index

Read the technical paper

COVID-19 is an acute respiratory disease that has been classified as a pandemic by the World Health Organization. Characterization of this disease is still in its early stages; however, it is known to have high mortality rates, particularly among individuals with preexisting medical conditions…

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ClosedLoop White paper

Developers

Download the open source version of the C-19 Index package via Github or PyPi. If you like this project, please remember to star us on Github!

Download From GitHub
Download From PyPi

Frequently Asked Questions

What is the C-19 Vulnerability Index (CV19_Index)?

The CV19 Vulnerability Index (CV19 Index) is an open source, AI-based predictive model that identifies people who are likely to have a heightened vulnerability to severe complications from COVID-19 (commonly referred to as “The CoronaVirus”). The CV19 Index is intended to help hospitals, federal / state / local public health agencies and other healthcare organizations in their work to identify, plan for, respond to, and reduce the impact of COVID-19 in their communities.

To be absolutely clear – the CV19 Index does NOT predict who will become infected with COVID-19 or geographic locations where the virus might spread. It is meant to identify people with a heightened risk of severe complications should they become infected.

Why is a Vulnerability Index Important?

The risk of death has been difficult to calculate, but a small study of people who contracted Covid-19 in Wuhan suggests that the risk of death increases with age, and is also higher for those who have diabetes, disease, blood clotting problems, or have shown signs of sepsis.   With an average death rate of 1%, the death rate rose to 6% for people with cancer, high blood pressure and chronic respiratory disease, 7% for people with diabetes, and 10% for people with heart disease. There was also a steep age gradient; the death rate among people aged 80+ was 15%.

What conditions are included in the proxy endpoint?

The proxy endpoint includes diagnosis codes for Pneumonia, Influenza, Acute Bronchitis, and Other Respiratory Infections.  They are specified using ICD-10-CM codes from International Classification of Diseases, 10th Revision, Clinical Modification and CCS categories from AHRQ’s Clinical Classifications Software CCS.

These endpoints are consistent with WHO guidelines and clinical papers that describe COVID-19 and its impacts.

What risk factors, or “features" did you use in the model?

The CV19 Index uses medical claims data that reflects an individual’s medical history, chronic conditions, comorbidities, prior adverse events, recent medical treatments and procedures, functional limitations, and degree of frailty.  It also integrates publicly-available data for several social determinants of health. More details on risk factors, known as “features” used in the model, such as Continuity of Care, Hospital Acquired Infections, and Fall-Related Injuries, along with other supporting technical details are available in the white paper here.

What is ClosedLoop doing to make sure the COVID-19 Index software is secure?

ClosedLoop has partnered with Ion Channel to ensure that COVID-19 Index code is continuously analyzed. The code and all its dependencies are checked for viruses, vulnerabilities and other risks every time the code is updated and no less frequently than once a day. New code, either from ClosedLoop developers or community contributors, all meet security criteria to be approved for addition to the code base.

Ion Channel is a software supply chain logistics and assurance platform that continuously monitors software used in critical infrastructure.  Continuous monitoring gives customers immediate notice of vulnerabilities in vendor products and open source software and measures suppliers’ time-to-response when remediation is required.

Is this HIPAA Compliant?

Use of the CV19 Index in the ClosedLoop cloud hosted environment is HIPAA compliant.  This requires a signed Business Associate Agreement, or BAA, available through the download and deploy process.

How do I deploy the CV19 Vulnerability Index?

We are offering three deployment models

  1. Download the CV19 Index code at https://github.com/closedloop-ai/cv19index and run the code on your infrastructure to deploy the model.
  2. Subscribe to the “CV19 Vulnerability Index” Mode Package on AWS Sagemaker to launch an instance of the model within your own AWS environment..
  3. Use the CV19 Vulnerability Index on our multi-tenant HIPAA compliant cloud hosted environment.

What can I do with the results of the CV19 Vulnerability Index?

We are on a mission to mobilize health care systems to more effectively target their efforts to protect the vulnerable members of their community. Creating the CV19 Index is just the start. We need your help to truly make a difference.  We need your help if it’s going to actually make a difference.  Let us know how you would like to get involved. Specific areas where help is needed will be updated soon.  In the meantime, please email covid19-info@closedloop.ai if you have questions or would like to help support these efforts.